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ic 50 calculation with graphpad prism 7 software  (GraphPad Software Inc)

 
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    GraphPad Software Inc ic 50 calculation with graphpad prism 7 software
    Effect of TROP2-targeted ADC on proliferation of KS-EMPD-1 cells. KS-EMPD-1 cells were treated with vehicle control (PBS) or various concentrations (0.1–100 μM) of <t>sacituzumab</t> (anti-TROP2 antibody) or sacituzumab <t>govitecan</t> (TROP2-targeted ADC) for 48 h. Then, viable cells were quantified using CCK-8 solution. Experiments were performed in triplicate wells and independently repeated three times. Mean ± SD of fold change of viable cells is shown. *** p < 0.001.
    Ic 50 Calculation With Graphpad Prism 7 Software, supplied by GraphPad Software Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/ic 50 calculation with graphpad prism 7 software/product/GraphPad Software Inc
    Average 90 stars, based on 1 article reviews
    ic 50 calculation with graphpad prism 7 software - by Bioz Stars, 2026-03
    90/100 stars

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    1) Product Images from "A multicenter study on TROP2 as a potential targeted therapy for extramammary Paget disease in Japan"

    Article Title: A multicenter study on TROP2 as a potential targeted therapy for extramammary Paget disease in Japan

    Journal: Scientific Reports

    doi: 10.1038/s41598-024-84566-y

    Effect of TROP2-targeted ADC on proliferation of KS-EMPD-1 cells. KS-EMPD-1 cells were treated with vehicle control (PBS) or various concentrations (0.1–100 μM) of sacituzumab (anti-TROP2 antibody) or sacituzumab govitecan (TROP2-targeted ADC) for 48 h. Then, viable cells were quantified using CCK-8 solution. Experiments were performed in triplicate wells and independently repeated three times. Mean ± SD of fold change of viable cells is shown. *** p < 0.001.
    Figure Legend Snippet: Effect of TROP2-targeted ADC on proliferation of KS-EMPD-1 cells. KS-EMPD-1 cells were treated with vehicle control (PBS) or various concentrations (0.1–100 μM) of sacituzumab (anti-TROP2 antibody) or sacituzumab govitecan (TROP2-targeted ADC) for 48 h. Then, viable cells were quantified using CCK-8 solution. Experiments were performed in triplicate wells and independently repeated three times. Mean ± SD of fold change of viable cells is shown. *** p < 0.001.

    Techniques Used: Control, CCK-8 Assay



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    Effect of TROP2-targeted ADC on proliferation of KS-EMPD-1 cells. KS-EMPD-1 cells were treated with vehicle control (PBS) or various concentrations (0.1–100 μM) of sacituzumab (anti-TROP2 antibody) or sacituzumab govitecan (TROP2-targeted ADC) for 48 h. Then, viable cells were quantified using CCK-8 solution. Experiments were performed in triplicate wells and independently repeated three times. Mean ± SD of fold change of viable cells is shown. *** p < 0.001.

    Journal: Scientific Reports

    Article Title: A multicenter study on TROP2 as a potential targeted therapy for extramammary Paget disease in Japan

    doi: 10.1038/s41598-024-84566-y

    Figure Lengend Snippet: Effect of TROP2-targeted ADC on proliferation of KS-EMPD-1 cells. KS-EMPD-1 cells were treated with vehicle control (PBS) or various concentrations (0.1–100 μM) of sacituzumab (anti-TROP2 antibody) or sacituzumab govitecan (TROP2-targeted ADC) for 48 h. Then, viable cells were quantified using CCK-8 solution. Experiments were performed in triplicate wells and independently repeated three times. Mean ± SD of fold change of viable cells is shown. *** p < 0.001.

    Article Snippet: IC 50 of sacituzumab govitecan was calculated with GraphPad Prism 7 software (GraphPad Software, San Diego, CA).

    Techniques: Control, CCK-8 Assay